EU Approves Glucose Oxidase from Aspergillus tubingensis for Food Production

On March 04, 2025, the European Union approved the “Use of the food enzyme Glucose oxidase from Aspergillus tubingensis strain GOX” amended Regulation (EC) No 1332/2008.

The key points are as follows:

• Glucose oxidase from non-GMO strain is approved for safe use in food processing;
• Authorized for use in egg processing, baked goods, cereal-based products, and brewed products to enhance quality and stability;
• Genotoxicity and 90-day toxicity study in rats confirmed no adverse effects at the highest tested dose (2000 mg TOS/kg body weight/day); 
• A match with a known contact allergen was found, but the risk of allergic reactions from dietary exposure is considered low; 
• The highest estimated exposure 1.555 mg TOS/kg body weight/day ensures a large safety margin of 1286 meeting EU microbiological and heavy metal standards.